Actinic Keratosis: Or something else? Differential Diagnosis

Skin and subcutaneous (L00-L99).

  • Arsenic keratosis – skin damage resulting in dryness and yellowish discoloration of the skin.
  • Benign lichenoid keratosis – form of keratosis in which there is the formation of nodules.
  • Discoid lupus erythematosus – form of lupus erythematosus limited to the skin.
  • Lentigo solaris (age spots).
  • Lichen ruber planus* (nodular lichen)
  • Psoriasis vulgaris* (psoriasis)
  • Seborrheic eczema* – greasy, scaly inflammation of the skin. It occurs mainly in areas of the skin where there are many sebaceous glands, such as the hairy head, face and trunk.
  • Seborrheic keratosis (synonyms: seborrheic wart, age wart, verruca seborrhoica), flat; most common benign (benign) tumor of the skin; initial cells of this cornification disorder are keratinocytes.
  • Tinea corporis* – chronic fungal skin disease affecting the whole body.

Musculoskeletal system and connective tissue (M00-M99).

  • Lupus erythematosus chronicus discoides – form of autoimmune disease that leads to the formation of disc-shaped erythema.

Neoplasms – tumor diseases (C00-D48).

  • Basal cell carcinoma (BCC; basal cell carcinoma) – semimalignant neoplasm of the skin that grows locally destructive, but very rarely metastasizes.
  • Extramammary M. Paget – Paget’s disease occurring outside the breast (malignant neoplasm of the female breast).
  • Lentigo maligna – slow-growing pigment spot, which is considered precancerous (precancerous).
  • Melanoma in situ – melanomas that have not yet broken through the so-called basement membrane – the boundary between the epidermis (epidermis) and dermis (dermis).
  • Bowen’s disease – precancerous (precancerous) squamous cell carcinoma of the skin; clinical picture: there are individual sharply defined but irregularly shaped, broad red-scaly skin lesions erythrosquamous or psoriasiform plaques (size varies from millimeters to decimeters). The skin changes are similar to psoriasis (psoriasis), but usually occurs only a single focus
  • Nevus cell nevus – benign skin tumor; mole.
  • Squamous cell carcinoma of the skin

* Inflammatory dermatoses (skin diseases) that can mimic the appearance of actinic keratosis, especially in early stages.