Actinic Keratosis: Prevention

To prevent actinic keratosis (AK), attention must be paid to reducing individual risk factors.

Behavioral risk factors

  • Consumption of stimulants
    • Tobacco (smoking)
  • Recreational or occupational exposure to UV radiation (UV-A rays (315-380 nm), UV-B rays (280-315 nm); sun; solarium.

Environmental exposure – intoxications (poisonings).

  • Damage to the skin by UV radiation (UVA, UVB; sun; solarium); recognized occupational disease (occupational disease list, BK list) in the presence of multiple actinic keratoses of the skin by UV radiation.
  • Infrared radiation
  • X-ray radiation/ionizing radiation
  • Anthracene
  • Arsenic
  • Benzpyrene
  • Crude kerosene wax
  • Carbon black
  • Tar products (lignite tar/lignite workers) and other hydrocarbons.

Every patient with statutory health insurance is entitled to skin cancer screening every 2 years from the age of 35. Routine skin self-examination (“skin self-examination”, SSE) is also desirable.

Prevention factors (protective factors)

  • Behavioral factors
    • Avoidance of strong sunlight (stay outdoors between 11 am and 3:00 pm to avoid UV index).
    • Wearing suitable clothing, sunglasses
    • Application of sunscreen UV sunscreen).
  • Patients with previously 2 non-melanoma skin cancers in the past 5 years: In one study, these patients were treated with 500 mg nicotinamide (vitamin B 3) 2 times daily for 1 year or with placebo, with follow-up examinations at 3-month intervals. Patients treated with nicotinamide had 11% fewer actinic keratoses than patients in the placebo group after 3 months, 14% after 6 months, 20% after 9 months and 11% after 12 months.

Secondary prevention

  • Early skin cancer detection (skin cancer screening) using dermoscopy (reflected light microscopy; increases diagnostic confidence).
  • Self-examinations