Acute Lymphoblastic Leukemia: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps:

  • General physical examination – including blood pressure, pulse, body temperature, body weight, body height; furthermore:
    • Inspection (viewing).
      • Skin, mucous membranes, and sclerae (white part of eye) [night sweats; pale skin color].
      • Lymph node stations (cervical, axillary, supraclavicular, inguinal) [lymphadenopathy (lymph node enlargement)?]
      • Abdomen (abdomen):
        • Shape of the abdomen?
        • Skin color? Skin texture?
        • Efflorescences (skin changes)?
        • Pulsations? Bowel movements?
        • Visible vessels?
        • Scars? Hernias (fractures)?
      • Genital [painless, usually unilateral swelling of the testis.]
      • Extremities [pain (especially in legs; “child may not walk”); bone pain; arthralgia (joint pain)]
    • Palpation (palpation) of lymph node stations (cervical, axillary, supraclavicular, inguinal) [lymphadenopathy (lymph node enlargement)?]
    • Auscultation (listening) of the heart [due topossible secondary disease: cardiomyopathy (heart muscle disease)]
    • Auscultation of the lungs [dyspnea (shortness of breath)]
    • Abdominal examination [hepatosplenomegaly (liver and spleen enlargement)?]
      • Percussion (tapping) of the abdomen.
        • Meteorism (flatulence): hypersonoric tapping sound.
        • Attenuation of tapping sound due to enlarged liver or spleen, tumor, urinary retention?
        • Hepatomegaly (liver enlargement) and/or splenomegaly (spleen enlargement): estimate liver and spleen size.
      • Palpation (palpation) of the abdomen (abdomen) (tenderness?, knocking pain?, coughing pain?, defensive tension?, hernial orifices?, renal bearing knocking pain?).
  • If necessary, urological / nephrological examination [due topossible sequelae: renal insufficiency / uremia (kidney weakness / kidney failure)].
  • Health check (as an additional follow-up measure).

Square brackets [ ] indicate possible pathological (pathological) physical findings.