A comprehensive clinical examination is the basis for selecting further diagnostic steps:
- General physical examination – including blood pressure, pulse, body weight, height; further:
- Inspection (viewing).
- Skin [female gender: male pattern of hair (upper lip beard, hair on chest), oily skin, acne vulgaris; premature pubic hair]
- Breast development [female sex: lack of breast development]
- Lack of pubertal development in both sexes.
- Genital area
- Girl/woman [clitoral hypertrophy (enlargement of the clitoris)]
- Boy/Male [hypogonadism (gonadal hypofunction), i.e. testicular atrophy/small testes, as opposed to increased development of secondary sexual characteristics (pubic hair and penis growth]
- Auscultation (listening) of the heart.
- Auscultation of the lungs
- Palpation (palpation) of the abdomen (abdomen) (tenderness?, knocking pain?, coughing pain?, defensive tension?, hernial orifices?, kidney bearing knocking pain?)
- Inspection (viewing).
- Cancer screening – due todifferential diagnoses: gonadal tumor (gonads: male and female gonads (ovaries/ovaries, testes))?, androgen-forming adrenal tumors (extremely rare).
- Health check
Square brackets [ ] indicate possible pathological (pathological) physical findings.