Alizapride

Products

Alizapride is commercially available in tablet form and as a solution for injection (Vergentan). The drug is not registered in many countries.

Structure and properties

Alizapride (C16H21N5O2, Mr = 315.4 g/mol) is structurally related to metoclopramide.

Effects

Alizapride (ATC A03FA05) has prokinetic and antiemetic properties. The effects are due to antagonism at dopamine receptors in the vomiting center.

Indications

For the prevention and treatment of vomiting, nausea, and emesis associated with cytostatic or radiation therapy and surgery.