Amenorrhea: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate amenorrhea:

Leading symptom

  • Primary amenorrhea: absence of menarche (first menstrual period):
    • Until after the age of 14 (in the absence of pubertal development) or.
    • Until after the age of 16 (when pubertal development has already begun).
  • Secondary amenorrhea: no menstrual bleeding for > 90 days with already established cycle.

Warning signs (red flags)

  • Anamnestic information:
    • Abnormal weight loss (> 10%) → think of: Anorexia nervosa
    • Excessive training / competitive sports
  • Visual disturbances/facial field defects (bitemporal hemianopsia/visual disturbance with loss of both temporal visual fields) or other neurological symptoms (e.g., headache) and cranial nerve compression Nausea (nausea)/vomiting → think of: Pituitary tumor (tumor of the pituitary gland; e.g., prolactinoma).