1st order laboratory parameters – obligatory laboratory tests.
- Small blood count
- Differential blood count
- HCG (human chorionic gonadotropin) determination – to rule out pregnancy.
- FSH (follicle-stimulating hormone).
- LH (luteinizing hormone)
- Prolactin
- TSH (thyroid-stimulating hormone)
- Testosterone
- 17-Beta-estradiol
Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.
- Inflammatory parameters – CRP (C-reactive protein).
- Fasting glucose (fasting blood sugar)
- Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin.
- Renal parameters – urea, creatinine, cystatin C or creatinine clearance, if necessary.
- Testosterone, cortisol, glucose, insulin, oral glucose tolerance test (oGTT) and HbA1c – due tosuspicion of polycystic ovary syndrome.
- Progestin test – control of the reaction of the endometrium (endometrium) [interpretation: see below progestin test].
- Estrogen test (progestin-estrogen test) – is performed in the absence of bleeding after the progestin test; for the estrogen test, the patient takes an estrogen-progestin combination (eg: Femoston) [interpretation: see below estrogen test].
- Clomiphene test – functional test of the hypothalamus (a small area in the diencephalon).
- GnRH test – testing the pituitary capacity (response of the pituitary gland).
- Gonadotropin test – testing the responsiveness of the ovaries (ovaries).
- TRH test – control of thyroid function.
- Dexamethasone inhibition test – if Cushing’s disease is suspected.
- DHEAS determination (dehydroepiandrosterone sulfate) – for adrenal cortical diagnostics.
- Chromosome analysis (due toeg VD Turner syndrome).
Note
- For classification of amenorrhea, see “World Health Organization (WHO) classification of amenorrhea” under Classification.