Effects
Aminoglycosides (ATC J01G) have bactericidal properties. They inhibit protein synthesis by bacteria by binding to subunits of ribosomes.
Indications
- Bacterial infectious diseases
- Special indications (paromomycin)
Active ingredients
- Amikacin
- Framycetin (= neomycin B)
- Gentamicin
- Neomycin
- Netilmicin
- Kanamycin (veterinary drug)
- Paromomycin
- Streptomycin
- Tobramycin, tobramycin inhalation, tobramycin eye drops.
Aminoglycosides are not available perorally as polycations and are administered topically or parenterally. Paromomycin is taken perorally but acts locally in the intestine.