Ampho-Moronal® contains the active ingredient Amphotericin B, and is a prescription-only drug. This drug is a so-called antimycotic. This means that it is used in case of fungal infections, especially yeast or mould infections. These can occur in the mouth and throat area (thrush), on the skin, in the intestine, the respiratory tract and in the genital area. Certain medications, such as glucocorticoids, cytostatics or antibiotics, can promote the growth of fungi by damaging protective barriers such as the mucous membrane of the mouth, throat or intestine or by generally reducing the immune defence.

Use and pharmaceutical form

Ampho-Moronal® is available in the form of tablets, lozenges, and as a suspension (solid dissolved in liquid). Ampho-Moronal® in tablet form is used for the therapy of a yeast infection in the intestine (candidosis), or to prevent a fungal infection, which can occur as a side effect of e.g. a cytostatic drug treatment in the context of cancer therapy. Lozenges are indicated for local treatment of an oral infection.

The administration of tablets to children must be carefully considered, as there are no clinical studies for the use of Ampho-Moronal® in children under 18 years of age. It is also used as a preventive measure for newborns whose mothers suffer from yeast infections of the vagina or diabetes. Suspensions are not recommended for use in premature infants.

Side effects and precautions

Before taking Ampho-Moronal® it must be ensured that there is no hypersensitivity to the active substance Amphotericin B or other components of the medication. Ampho-Moronal® is not suitable in case of a systemic infection, i.e. an infestation of the internal organs. When taken orally, side effects are less frequent in comparison, but they cannot be ruled out.

In rare cases, other undesirable effects may occur, such as a reduction in the ability to drive and operate machines. In pregnant women or breastfeeding patients, the administration must be carefully considered, as not much information is available yet, for example whether the active substance passes into breast milk. – Inflammation of the mucous membrane of the tongue,

  • Nausea,
  • Vomiting
  • Or even diarrhea. – Hives (blistering and reddening of the skin, as in contact with nettles)
  • Angioedema (quickly beginning, painless swelling of the subcutis),
  • Flatulence,
  • Furry feeling of the entire tongue,
  • Inflammation of the oral mucosa (stomatitis),
  • Dry mouth,
  • Dizziness and insomnia have been reported.