Anal Itching (Pruritus Ani): Drug Therapy

Therapeutic targets

  • Relief of itching
  • Elimination of the cause

Therapy recommendations

  • Symptomatic therapy: agents for topical application (see below).
  • Specific therapy: e.g., antibiotics, antifungals (antifungal agents), anthelmintics (anthelmintics), chemotherapeutic agents, etc.
  • In the interval use of nourishing creams to avoid an occlusive situation (air- and water-impermeable covering of skin areas).

Active ingredients (main indication) for topical use

Active ingredient group Active ingredients
Glucocorticoids Dexamethasone, hydrocortisone
Calcineurin inhibitors Tacrolimus
Cannabinoid agonist Palmitoylethanolamine
Capsaicin Capsaicin cream 0.025-0.075 %
Menthol Menthol 3 %
Urea Urea cream