The following are the most important diseases or complications that may be contributed to by anaphylaxis:
Respiratory system (J00-J99)
- Bronchospasm – cramping of the muscles surrounding the airways.
- Rhinitis (inflammation of the nasal mucosa).
Skin and subcutaneous (L00-L99)
- Urticaria (hives; anaphylactic reaction: 15-20 min; IgE-mediated: 6-8 h).
Injuries, poisonings, and other sequelae of external causes (S00-T98).
- Anaphylactic shock – shock resulting from a severe allergic reaction (usually as a mast cell-dependent allergic immediate reaction (type I, IgE-mediated; primarily from insect venoms, foods, and drugs) that results in disruption of peripheral circulatory regulation with relative volume depletion due to increased capillary permeability
- Quincke’s edema, also known as angioedema – often massive swelling of the subcutis (subcutaneous tissue) or submucosa (submucosal connective tissue), which usually affects the lips and eyelids, but can also affect the tongue or other organs.
The following are the main diseases or complications that may be co-morbid due to anaphylactic shock:
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).
- Multi-organ failure (MODS, multi-organ dysfunction syndrome; MOF: multi-organ failure) – simultaneous or sequential failure or severe functional impairment of various vital organ systems of the body.
