To prevent aneurysm, attention must be paid to reducing individual risk factors.
Aneurysm of the vessels supplying the brain
Behavioral risk factors
- Alcohol abuse
- Nicotine abuse (applies to both sexes)
- Proportion of female smokers with intracranial (“localized within the skull”) aneurysms is about four times higher than among women without aneurysms
Prevention factors
- Genetic factors:
- Genetic risk reduction depending on gene polymorphisms:
- Genes/SNPs (single nucleotide polymorphism):
- SNP: rs10757278 in an intergenic region.
- Allele constellation: AA (0.77-fold).
- SNP: rs10757278 in an intergenic region.
- Genes/SNPs (single nucleotide polymorphism):
- Genetic risk reduction depending on gene polymorphisms:
- Medications: It is possible that therapy with acetylsalicylic acid (ASA; at least 81 mg daily) slows the growth of intracranial aneurysms (brain aneurysms).
Thoracic aortic aneurysm
Behavioral risk factors
- Nicotine abuse
Abdominal aortic aneurysm
Behavioral risk factors
- Nicotine abuse (for older male smokers or ex-smokers, routine screening for early detection of abdominal aortic aneurysm is recommended!)
Note: All men over 65 years of age in Germany are recommended abdominal aortic aneurysm screening (BAA screening). The prevalence (disease incidence) of BAA is 1.5% annually. The mortality (death rate) of ruptured abdominal aortic aneurysm (BAA) is high, as high as 80%.
Prevention Factors
- Genetic factors:
- Genetic risk reduction depending on gene polymorphisms:
- Genes/SNPs (single nucleotide polymorphism):
- SNP: rs10757278 in an intergenic region [cerebral aneurysm and abdominal aortic aneurysm].
- Allele constellation: AA (0.77-fold).
- SNP: rs10757278 in an intergenic region [cerebral aneurysm and abdominal aortic aneurysm].
- Genes/SNPs (single nucleotide polymorphism):
- Genetic risk reduction depending on gene polymorphisms:
