Aneurysm cannot be diagnosed by laboratory parameters. The following 1st-order laboratory parameters-obligatory laboratory tests-should nevertheless be determined.
- Small blood count
- Fasting glucose (fasting blood glucose)
- Inflammatory parameters – CRP (C-reactive protein).
- Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin.
- Renal parameters – urea, creatinine, cystatin C or creatinine clearance, if necessary.
- Coagulation parameters – PTT, Quick
- Cholesterol – total cholesterol, LDL cholesterol, HDL cholesterol.
- Triglycerides
- D-dimers (end product of proteolysis of fibrin) – if pulmonary embolism is suspected (see also under “Pulmonary Embolism/Physical Examination” Wells score to determine the clinical probability of pulmonary embolism); negative predictive value 99.3%, thus suitable for screening! Note: In the presence of acute aortic dissection, median D-dimers were 5,810 ng/ml, compared with only 370 ng/ml in patients with exclusion of aortic syndrome; sensitivity (percentage of diseased patients in whom the disease is detected by use of the procedure, ie. i.e., a positive finding occurs) 100%, specificity (probability that actually healthy people who do not have the disease in question are also detected as healthy in the test) of a positive D-dimer test for the detection of acute aortic syndrome was 96.7% with a specificity (probability that actually healthy people who do not have the disease in question are also detected as healthy in the test) of 64%; negative predictive value was 99.2
- Highly sensitive cardiac troponin T (hs-cTnT) or troponin I (hs-cTnI) – for suspected myocardial infarction (heart attack).
