Products
Antazoline is fixed combination with tetryzoline in the form of eye drops commercially available (Spersallerg, Spersallerg SDU). It has been approved in many countries since 1967.
Structure and properties
Antazoline (C17H19N3, Mr = 265.35 g/mol) is present in drugs as antazoline hydrochloride, a white crystalline powder that is sparingly soluble in water. It is also present in some drugs as antazoline sulfate. Antazoline is an aniline and imidazole derivative.
Effects
Antazoline (ATC R01AC04, ATC R06AX05) has antihistamine and antallergic properties. The effects are due to competitive antagonism at histamine H1 receptors. This reverses the effects of histamine, which is involved in the development of the allergic reaction.
Indications
For the treatment of allergic conjunctivitis.
Dosage
According to the expert information. The drops are placed in the conjunctival sac.
