Definition
Plant antraceene derivatives with the common structural feature 1,8-dihydroxyanthrone. Numerous derivatives (anthrones, anthranols, anthraquinones, dianthrones, naphthodianthrones). 1,8-Dihydroxyanthrone:
Effects
- Laxative (Prodrugs)
- Antidepressant: St. John’s wort
- Antiarthrotic: Rhine, Diacerein (Verbonil).
- Cytotoxic: mitoxantrone (Novantrone).
Indications
- Primarily for short-term treatment of constipation.
- Bowel emptying
- Some: Osteoarthritis
Medicinal drugs
- Aloe: e.g. aloin A
- American rotten tree (Cascara bark)
- Sloth tree
- Buckthorn
- Rhubarb
- Senna
