Antiarrhythmics

Indications

For the treatment of cardiac arrhythmias.

Active ingredients

Class I (sodium channel blockers): class IA:

• Ajmaline (off-label).
• Quinidine (out of trade)
• Procainamide (out of commerce)

Class IB:

• Lidocaine
• Phenytoin (not approved for this indication in many countries).
• Tocainide (not commercially available in many countries).
• Mexiletine (not on sale in many countries).

Class IC:

• Encainid (Enkaid, out of trade).
• Flecainide (Tambocor)
• Propafenone (Rytmonorm)

Class II (beta blockers):

• Beta blocker

Class III (potassium channel blockers):

• Amiodarone (Cordarone, generic).
• Dronedarone (Multaq)
• Ibutilide (Corvert, out of commerce).
• Sotalol (generic, original: Sotalex).

Class IV (calcium channel blockers):

• Verapamil (Isoptin, generic).
• Diltiazem (Dilzem, generics)

Other:

• Adenosine (crenosine)
• Cardiac glycosides: digoxin (Digoxin Sandoz).
• Vernakalant (Brinavess, Class I and III).