Avanafil therapy is a drug treatment for erectile dysfunction (ED).
Indications (areas of application)
- Erectile dysfunction
Contraindications
- Patients who have had a myocardial infarction (heart attack), apoplexy (stroke), or life-threatening arrhythmia within the past 6 months,
- Patients with persistent hypotension (blood pressure < 90/50 mmHg) or hypertension (blood pressure > 170/100 mmHg).
- Patients with unstable angina, angina during intercourse, or congestive heart failure (congestive heart failure) stage 2 or higher, as classified by the New York Heart Association (NYHA)
- Patients with severe hepatic impairment (Child-Pugh stage C).
- Patients with severe renal impairment (creatinine clearance < 30 ml/min).
- Patients experiencing loss of vision in one eye due to nonarteritic anterior ischemic optic neuropathy (NAION), whether or not this episode is related to prior exposure to a phosphodiesterase 5 (PDE5) inhibitor
- Patients with known hereditary degenerative retinopathies (retinal diseases),
- Patients using potent CYP3A4 inhibitors (including ketoconazole, ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, and telithromycin).
Drug interactions and other interactions (avanafil must not be co-administered with nitrates (NO donors) and other possible drug interactions must be considered: see the SmPC).
Possible side effects
- Common: headache (7%), feeling hot, nasal congestion.
- Occasional: dizziness, somnolence, sinus pain, blurred vision, palpitations (heart palpitations), flushing, exertional dyspnea (shortness of breath on exertion), dyspepsia (irritable stomach), nausea, vomiting
Further notes
Erectile dysfunction is a euphemism for a man’s limb stiffness not being sufficient for sexual intercourse, and thus the man’s inability to penetrate his partner with his penis.
Men of all ages can be affected and the causes of erectile dysfunction are very diverse.
Erectile dysfunction can occur in:
- Atherosclerosis (arteriosclerosis, hardening of the arteries).
- Hypertension (high blood pressure)
- Diabetes mellitus
- Hormonal disorders
- Excessive consumption of alcohol, cigarettes and drugs.
- Partnership problems
- Mental upsets
The active ingredient avanafil is taken as a tablet by the patient before sexual intercourse, and sexual intercourse can be performed after the onset of action with sufficient limb rigidity.
Avanafil therapy can also be combined with psychological counseling and psychotherapy.
Benefits
Avanafil prevents erectile dysfunction, thereby restoring your natural vitality.
This leads to great mental and psychological relief.You can once again enjoy a satisfying sex life and have a gain in quality of life.
