Products
Bamipin is commercially available in Germany and Austria as a gel for topical use (Soventol). The drug is not registered in many countries.
Structure and properties
Bamipin (C19H24N2, Mr = 280.4 g/mol) is a piperidineamine derivative. In the drug product, it is present as racemate and bamipine lactate.
Effects
Bamipin (ATC D04AA15) has antihistamine, antipruritic, antidepressant, and antiallergic properties. The effects are due to antagonism at histamine H1 receptors.
Indications
For symptomatic treatment of insect bites.
Dosage
According to the package leaflet. The gel is applied thinly or lightly massaged several times a day.
Contraindications
Bamipin is contraindicated in case of hypersensitivity and during pregnancy and lactation. For complete precautions, see the drug label.
Interactions
Drug-drug interactions have not been reported to date.
Adverse effects
Possible adverse effects include hypersensitivity reactions and a mild burning sensation after application. Cutaneous absorption is possible with large-area administration and may result in central nervous side effects such as fatigue.
