1st order laboratory parameters – obligatory laboratory tests.
- Small blood count
- Differential blood count
- Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate).
- Electrolytes – calcium, phosphate
- Alkaline phosphatase (AP) – if bone changes such as bone metastases, osteoporosis (bone loss), osteomalacia (bone softening), etc. are suspected.
- Renal parameters – urea, creatinine, if necessary cystatin C or creatinine clearance.
- LDH
- Uric acid
Laboratory parameters 2nd order – depending on the results of the history, physical examination and obligatory laboratory parameters – for differential diagnostic clarification.
- Serological examination – if infectious genesis is suspected.
- Urine status (rapid test for: pH, leukocytes, nitrite, protein, glucose, ketone, urobilinogen, bilirubin, blood), sediment, if necessary urine culture (pathogen detection and resistogram, i.e. testing of suitable antibiotics for sensitivity/resistance).
- Parathyroid parameters – parathyroid hormone (PTH), vitamin D3 (25-OH vitamin D), calcium – if hyperparathyroidism (parathyroid hyperfunction) is suspected.
- Vitamin D (25-OH vitamin D), calcium – in suspected rickets (disorder of bone metabolism in children in the growth phase, which leads to pronounced demineralization of bone and skeletal changes due to retardation of bone growth).
- Biopsy (tissue sample) – when systemic mastocytosis (disease characterized by excessive proliferation of mast cells in internal organs/bone marrow) is suspected.
- Tumor marker determination – when malignant (malignant) process is suspected.
