Products
Bopindolol was commercially available in tablet form (Sandonorm). It had been approved in many countries since 1984 and was withdrawn from the market in August 2010. Currently, drugs containing bopindolol are no longer on the market in many countries. Another beta-blocker can be used as a substitute.
Structure and properties
Bopindolol (C23H28N2O3, Mr = 380.5 g/mol) is a prodrug that is metabolized in the liver by hydrolysis to the active drug.
Effects
Bopindolol (ATC C07AA17) is a nonspecific beta-blocker with moderate sympathomimetic intrinsic ISA, see under beta-blockers.
Indications
- Essential hypertension
- Angina pectoris
Dosage
According to the drug label. The usual dose is 1-2 mg per day. In severe renal insufficiency, the dose must be adjusted.
