Severe cases of xerostomia (dry mouth): saliva substitute solutions (e.g., Artisial, Glandosane, Oralube, Siccasan) as flavored or neutral substitutes, and oil rinses
Clonazepam (anticonvulsant / drug used to treat or prevent epileptic seizures); use only for a short time, ie 2-4 weeks (because of the risk of dependence)!
Alpha lipoic acid (endogenous substance that has important functions as a coenzyme).
Studies on other active substances still need to be done.
Secondary burning mouth syndrome (BMS; i.e., resulting from local or systemic disease(s) affecting an entire organ system).
Candidiasis (fungal infection):
Uncomplicated infections: topical (local) treatment with antifungal suspension (antifungal agent) or lozenges.
Complicated infections (eg, invasive candidamycosis, aspergillosis): systemic therapy 7-10 days with eg, fluconazole or other azoles.
Food allergies or allergies to food components such as preservatives → see below food allergies.
Mucosal trauma (mucosal injury) caused by ill-fitting dentures or decayed teeth → dental treatment.
Radiation mucositis (radiation-induced inflammation of the oral mucosa): artificial saliva substitute solution (see above) and analgesic mouth rinses (e.g., 1.5 mg/ml with lidocaine hydrochloride and dexpanthenol, NRF 7.15., solution for use in the oral cavity)
