Busulfan

Products

Busulfan is commercially available as a concentrate for the preparation of an infusion solution (Busilvex). It has been approved in many countries since 2004.

Structure and properties

Busulfan (C6H14O6S2, Mr = 246.3 g/mol) exists as a white crystalline powder that is very sparingly soluble in water.

Effects

Busulfan (ATC L01AB01) has cytotoxic properties.

Indications

Conditioning before hematopoietic stem cell transplantation.