Products
Butizide was marketed exclusively in combination with spironolactone in the form of film-coated tablets (Aldozone). It had been approved in many countries since 1968.
Structure and properties
Buticide (C11H16ClN3O4S2, Mr = 353.8 g/mol)
Effects
Buticide (ATC C03EA14) has diuretic properties.
Indications
In combination with spironolactone:
- Heart failure
- Liver cirrhosis with ascites and/or edema.
- Nephrotic syndrome
- Essential hypertension