Buticide

Products

Butizide was marketed exclusively in combination with spironolactone in the form of film-coated tablets (Aldozone). It had been approved in many countries since 1968.

Structure and properties

Buticide (C11H16ClN3O4S2, Mr = 353.8 g/mol)

Effects

Buticide (ATC C03EA14) has diuretic properties.

Indications

In combination with spironolactone:

  • Heart failure
  • Liver cirrhosis with ascites and/or edema.
  • Nephrotic syndrome
  • Essential hypertension