Cachexia: Drug Therapy

Therapy goals

  • Avoidance of complications
  • Appetite stimulation

Therapy recommendations

  • In drug therapy for the various forms of malnutrition, the underlying disease should first be identified and treated. Furthermore, nutritional counseling including nutritional analysis or therapy (if necessary, by means of a protein-energy supplement, ie, a fully balanced diet for the dietary treatmentof persons with catabolic metabolic state) is required.
  • Corticosteroids (prednisolone) and progestins (dydrogesterone) have a positive effect on appetite, as demonstrated by studies:
    • Corticosteroids improve appetite, decrease pain intensity, and simultaneously reduce existing nausea (sickness)
    • Progestins improve appetite and mood.
  • See also under “Other therapy“.