1st order laboratory parameters – obligatory laboratory tests.
- Small blood count
- Inflammatory parameters – CRP (C-reactive protein) or PCT (procalcitonin).
- Electrolytes – calcium, chloride, potassium, magnesium, sodium, phosphate.
- Fasting glucose (fasting blood glucose).
- Blood gas analysis (ABG) – for circulatory instability/shock; determination of:
- Lactate value (initial) and lactate clearance within 24 h – biomarkers in MICS patients (myocardial infarction (MI); cardiogenic shock (CS))[initial serum lactate drops from about 4 mmol/l to 2.5 mmol/l within 8 h and to 1.5-2 mmol/l within 24 h].
Laboratory parameters 2nd order – depending on the results of the history, physical examination and obligatory laboratory parameters – for differential diagnostic clarification.
- IgE, total allergen-specific IgE, anti-IgA.
- Tryptase (mast cell tryptase) – in suspected anaphylactic shock [values 20-200 μg/l; decrease to normal within 24-48 hours].
- Urine status (rapid test for: pH, leukocytes, nitrite, protein, glucose, ketone, urobilinogen, bilirubin, blood), sediment, if necessary urine culture (pathogen detection and resistogram, that is, testing of suitable antibiotics for sensitivity/resistance).
- Blood culture or blood cultures (without delay) – if septic shock is suspected.
- Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin.
- Renal parameters – urea, creatinine, cystatin C or creatinine clearance, if necessary.
- Coagulation parameters – PTT, Quick
- Toxicological tests – for suspected intoxications.
- Thyroid parameters – TSH
