Products
In many countries, there are currently no registered medicines containing the active ingredient Cathin. Products containing Cathine are not banned, but are subject to prescription and narcotics laws.
Structure
D-cathine (C9H13NO, Mr = 151.2 g/mol) is a natural substance from the cath (, Celastraceae), which is also produced synthetically. It is a hydroxylated amphetamine derivative (β-hydroxyamphetamine).
Effects
Cathine (ATC A08AA07) has indirect sympathomimetic, stimulant, and appetite suppressant properties. The effects are due to increased release of neurotransmitters. It has a short half-life of about three hours and is excreted primarily by the kidneys.
Indications
For supportive treatment of obesity (Germany).
Abuse
Cathine can be abused as a stimulant intoxicant and party drug. It is a doping agent banned in athletic competition.
Dosage
According to the professional information.
Contraindications
- Hypersensitivity
- Cardiovascular disease
- Anorexia nervosa
- Depression
- Tendency to abuse drugs, alcohol dependence.
- Pheochromocytoma
- Hyperthyroidism
- Narrow-angle glaucoma
- Concurrent treatment with other centrally acting appetite suppressants.
- Pregnancy and lactation
- Treatment of children
For complete precautions, see the drug label.
Interactions
Drug-drug interactions have been described with sympathomimetics, antidepressants, MAO inhibitors, antihypertensives, neuroleptics, and caffeine, among others.
Adverse effects
Possible adverse effects include:
- Habituation, dependence, withdrawal symptoms.
- Psychosis, depression, nervousness, restlessness, sleep disorders, dizziness.
- Seizures
- Palpitations, heart palpitations, high blood pressure, chest pain.
- Pulmonary arterial hypertension
- Severe cardiovascular disorders such as stroke, angina, myocardial infarction, and cardiac arrest
