The following are the major diseases or complications that may be contributed to by central sleep apnea syndrome (ZSAS):
Respiratory system (J00-J99)
- Pneumonia (inflammation of the lungs; due to nocturnal aspiration/intrusion of liquid or solid substances into the respiratory tract).
Cardiovascular system (I00-I99) Cardiovascular system (I00-I99).
- Arterial hypertension (high blood pressure).
- Atherosclerosis (arteriosclerosis, hardening of the arteries)
- Apoplexy (stroke)
- Triggering a myocardial infarction (heart attack) in the presence of coronary artery disease (CAD).
- Cor pulmonale (dilatation (widening) and/or hypertrophy (enlargement) of the right ventricle (main chamber) of the heart as a result of pulmonary hypertension (increased pressure in the pulmonary circulation)
- Cardiac arrhythmias (including atrial fibrillation (VHF) and sinus arrests/AV blocks).
- Coronary artery disease (CAD)
- Sudden cardiac death (PHT)
- Pulmonary hypertension (pulmonary hypertension)
Neoplasms – tumor diseases (C00-D48)
- Mammary carcinoma (breast cancer; 1.89-fold risk).
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99)
- Cephalgia (headache; morning holocephalic headache).
- Secondary polyglobulia (isolated elevated erythrocyte count (red blood cell count) with normal plasma volume)
- Daytime sleepiness/increased daytime sleepiness.
Further
- Increased mortality (death rate) from the underlying disease.
- High risk of accidents and injuries due to microsleep – 7 times higher accident rate than other motorized road users
