Cervical Cancer Definition

In cervical carcinoma – colloquially called cervical cancer – (synonyms: Adenocarcinoma of the collum uteri; malignant neoplasm of the cervix; malignant neoplasm of the cervix uteri; cervical carcinoma; cervical malignancy; carcinoma of the cervix uteri; carcinoma of the collum uteri; collum carcinoma (collum uteri); collum carcinoma of the uterus; Collum carcinoma of uterus; Malignancy of cervix uteri; Metastatic collum carcinoma (collum uteri); Squamous cell carcinoma of collum uteri; Portiocarcinoma; Portiocarcinoma, cervical; Portio-uteri malignancy; ICD-10-GM C53. -: Malignant neoplasm of the cervix uteri) is a malignant neoplasm in the area of the cervix uteri (neck of the uterus).

Cervical carcinoma is the most common malignant neoplasm of the female genitalia.

Definition of the nomenclature of cervical carcinoma (see below classification)

Incidence peak: there are two disease peaks, with the early peak occurring between the ages of 35 and 54 years and the late peak occurring after the age of 65 years. The incidence (frequency of new cases) for cervical cancer varies significantly worldwide. It varies from 3.6 women in Finland to 45 women in Colombia per 100,000 population per year. Worldwide, the incidence rate is assumed to be 15.2 per 100,000 population per year. The incidence in Germany is 11.2-13.3 cases per 100,000 population per year. Course and prognosis: If cervical carcinoma is detected at an early stage and the so-called depth of penetration into the tissue (invasion) is less than 3 mm, the chances of cure are almost 100%. Cervical carcinoma can be recurrent. Every third patient must expect a recurrence after primary therapy.

In Germany, approximately 1 in 340 women die from cervical carcinoma. In the 1980s, this figure was more than twice as high.The 5-year survival rate is around 90% for tumors treated early and then falls off stage by stage. In stage II, it is between 40-60%.

HPV vaccination, which is approved for all girls in Germany from age 9-17 and is covered by health insurance, represents a milestone in the prevention of cervical cancer.