Cervical Insufficiency: Complications

The following are the most important conditions that may be contributed to by cervical insufficiency (cervical weakness) or by prophylactic (e.g., cerclage/cervical wrap) and therapeutic (e.g., cerclage, bed rest, especially tocolysis/inhibition of labor) measures, as well as by premature delivery:

Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99).

  • Patent ductus arteriosus (synonyms: Called ductus arteriosus botalli, ductus botalli, or ductus arteriosus Harvey; provides a connection between the aorta (main artery) and truncus pulmonalis (“pulmonary trunk”) in the fetal (child) circulation). Incl: Patent ductus botalli, persistent ductus arteriosus (PDA) secondary to prematurity.

Respiratory system (A00-B99)

  • Pulmonary edema (water retention in the lungs) under tocolysis (labor inhibition) with betamimetics, especially in combination with glucocorticoids

Eyes and eye appendages (H00-H59).

  • Retinopathia praematurorum (RPM; synonyms: retrolental fibroplasia (RLF) or retinopathy of prematurity (retinal disease), retinopathy of prematurity (ROP).

Certain conditions originating in the perinatal period (P00-P96).

  • Respiratory distress syndrome [Respiratorydistress syndrome] of the newborn.
  • Enterocolitis necroticans (necrotizing enterocolitis/inflammatory bowel disease, NEC, NEK) in the fetus and neonate
  • Neonate with extreme immaturity, as a result of. : Gestational age (gestational age) of less than 28 completed weeks (of less than 196 completed days).
  • Damage to the fetus and newborn due to:
    • Chorioamnionitis (inflammation of the inner egg membrane and outer layer of amniotic sacs around the embryo or fetus/unborn child). Incl: Amnionitis, chorionitis, placentitis (inflammation of the placenta).
    • Birth weight less than 2,500 grams (increased perinatal morbidity and mortality/illness incidence and number of fetal deaths in the perinatal period/deaths and deaths by day 7 postpartum).
    • Oligohydramnios (amniotic fluid volume less than 500 ml) under tocolysis (labor inhibition) with prostaglandin antagonists
    • Premature rupture of the membranes
    • Other and unspecified morphologic and functional placental abnormalities. Incl: Placental dysfunction, infarction, insufficiency.
  • Other born before term, as a result of: gestational age (gestational age) of 28 or more completed weeks, but less than 37 completed weeks (from 196 completed days to less than 259 completed days). Incl: Premature birth o. n. a.

Endocrine, nutritional and metabolic diseases (E00-E90).

Cardiovascular System (I00-I99).

  • Hypotension (low blood pressure) caused by drugs under tocolysis (labor inhibition) with betamimetics, calcium antagonists, magnesium sulfate

Psyche – Nervous System (F00-F99; G00-G99).

  • Drug-induced tremor (shivering) during tocolysis (labor inhibition) with beta-mimetics.
  • Drug-induced headache, not elsewhere classified, under tocolysis with betamimetics, oxytocin antagonists (atosiban), calcium antagonists (nifedipine), magnesium sulfate
  • Nonorganic sleep disorder, unspecified, under tocolysis with betamimetics.

Pregnancy, childbirth, and puerperium (O00-O99).

  • Amniotic infection syndrome (English : amniotic infection syndrome, abbreviated as AIS; infection of the egg cavity, placenta, membranes, and possibly the fetus/unborn child during pregnancy or delivery with risk of sepsis (blood poisoning) to the child) (after cerclage surgery).
  • Thromboembolism (occlusion of a blood vessel by a detached blood clot) during the gestational period (due to bed rest as a result of cerclage surgery)
  • Deep vein thrombosis (DVT; complete or partial occlusion of a deep vein) during pregnancy (due to bed rest as a result of preterm labor)
  • Premature labor

Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).

  • Hyperglycemia (high blood glucose), unspecified, during tocolysis (labor inhibition) with betamimetics
  • Edema (water retention), unspecified. incl.: Fluid retention o. n. A, under tocolysis with betamimetics.
  • Palpitations (heart palpitations), incl.: Palpitations under tocolysis with beta-mimetics or calcium antagonists.
  • Restlessness and agitation under tocolysis with betamimetics.
  • Tachycardia (heartbeat too fast: > 100 beats per minute), unspecified during tocolysis with betamimetics
  • Nausea and vomiting during tocolysis with betamimetics, oxytocin antagonists (atosiban), prostaglandin antagonists, magnesium sulfate

Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99).

  • Unspecified renal insufficiency (renal weakness), incl.: Renal insufficiency not designated as acute or chronic, renal insufficiency o.n.s., uremia (occurrence of urinary substances in the blood above normal levels/renal failure) o.n.s. (decreased excretion under beta-mimetics and prostaglandin antagonists)

Further

  • Premature occlusion of the ductus arteriosus botalli under tocolysis with prostaglandin antagonists.