Chagas Disease (American Trypanosomiasis): Drug Therapy

Therapeutic targets

• Rehydration (fluid balance).
• Elimination of pathogens
• Avoidance of complications

Therapy recommendations

• In the acute phase: antiprotozoal agents.
• Rehydration – oral rehydration for signs of dehydration (fluid deficiency; > 3% weight loss): administration of oral rehydration solutions (ORL), which should be hypotonic, between meals (“tea breaks”) for mild to moderate dehydration.
• Compensation of electrolyte losses (blood salts).
• In the chronic phase, only symptomatic therapy can be performed.