Chagas Disease (American Trypanosomiasis): Test and Diagnosis

1st order laboratory parameters – obligatory laboratory tests.

  • Pathogen detection in blood, punctate, bone marrow, lymph node biopsy.
  • Serology [in case of detection of Ak against T. cruzi as well as corresponding clinical symptoms, direct pathogen detection should be aimed for].

Laboratory parameters 2nd order – depending on the results of the history, physical examination and the obligatory laboratory parameters – for differential diagnostic clarification.

  • Small blood count
  • Differential blood count
  • Inflammatory parameter – CRP (C-reactive protein)
  • Renal parameters – creatinine and urea.
  • Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT).
  • Coagulation parameters – PTT, Quick
  • CSF puncture (collection of cerebrospinal fluid by puncture of the spinal canal) for CSF diagnosis.
  • Blood cultures, smears from drains, etc.