Chlamydia: Test and Diagnosis

1st order laboratory parameters – obligatory laboratory tests.

  • Microscopic detection of the bacteria by immunofluorescence test (IFT).
  • Chlamydia trachomatis IgM, IgG, and IgA antibodies (only in chronic invasive infections).
  • Chlamydia PCR (molecular genetic method), this allows the reliable direct detection of the pathogen DNA from the secretion of the cervix or urine [material of first choice – men: first stream urine; women: Vaginal swab or cervical secretion (secretion of the cervix) and rectal swab].

Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.

  • Bacteria
    • Neisseria gonorrhoeae (gonorrhea, gonorrhea) – genital swab for pathogen and resistance, specifically for Neisseria gonorrhoeae.
    • Treponema pallidum (lues, syphilis) – antibodies against Treponema pallidum (TPHA, VDRL, etc.).
    • Ureaplasma urealyticum
  • Viruses
    • HIV (AIDS)
    • Herpes simplex virus type 1/2 (HSV type 1 u. 2)
    • Human papilloma virus [HPV] (Condylomata acuminata)
  • Fungi/Parasites
    • Fungi: Candida albicans et al. Candida species genital smear (pathogen and resistance).
    • Trichomonas vaginalis (trichomoniasis, colpitis) – antigen detection.

Chlamydia screening

Chlamydia screening is the examination of a urine sample using a nucleic acid amplifying test (NAT). This is done in Germany as part of prenatal care and before interruptions (abortions). Furthermore, since the decision of the G-BA in 2008, every woman under the age of 25 is entitled to one examination per year.