Products
Clofarabine is commercially available as a concentrate for the preparation of an infusion solution (Evoltra). The drug is not registered in many countries.
Structure and properties
Clofarabine (C10H11ClFN5O3, Mr = 303.7 g/mol) is a purine derivative.
Effects
Clofarabine (ATC L01BB06) is antitumoral and cytotoxic.
Indications
Acute lymphoblastic leukemia (ALL) in pediatric patients.