Coenzyme Q10 (CoQ10) from the ubiquinone group represents an important component of cellular energy supply (oxidative phosphorylation). It has its function in redox reactions in the respiratory chain. The organs with the highest energy requirements – such as the heart, lungs and liver – also have the highest Q-10 concentrations.
Coenzyme Q-10 is partly absorbed through food, but is also produced in the body itself.
Coenzyme Q10 is determined using high performance liquid chromatography (HPLC).
The method
Material needed
- Blood plasma (light protected)
- Blood serum (light protected)
Preparation of the patient
- Not necessary
Disruptive factors
- Light interference
Standard values
| Reference values | mg/l | μg/l |
| Man | 0,50-1,10 | 500-1.100 |
| Ms. | 0,45-1,05 | 450-1.050 |
Indications
- Arterial hypertension (high blood pressure).
- Heart failure (cardiac insufficiency)
- Cardiac arrhythmias, unspecified
- Coronary artery disease (CAD)
- Vitamin E deficiency
- Condition n. heart surgery, unspecified
Interpretation
Interpretation of increased values
- Not relevant to disease
Interpretation of lowered values
- Coenzyme Q10 deficiency
- Vitamin E deficiency
- Statin therapy (hydroxy-methyl-glutaryl-coenzyme A reductase inhibitors; HMG-CoA reductase inhibitors; statins).
Notice. It is likely that the above heart diseases may be co-caused by decreased levels of coenzyme Q10.
