Avalox® should not be administered to people who have a history of hypersensitivity to Avalox® of other similar antibiotics. In addition, it is recommended that Avalox® not be combined with non-steroidal anti-inflammatory drugs (NSAIDS) such as aspirin, ibuprofen or diclofenac, as this increases the risk of side effects in the central nervous system. Avalox® is contraindicated during pregnancy because the active ingredients contained in it can be transmitted to the unborn child via the placenta.
This can lead to a miscarriage or various birth defects in the child. In addition, Avalox® should not be taken while breastfeeding either, as Avalox® can also be transmitted to the child via breast milk. Avalox® should only be used by diabetics under strict control of their blood sugar levels, as the intake of Avalox® and the associated metabolic processes can cause blood sugar levels to fluctuate more than usual.
Furthermore, Avalox® is contraindicated in children to avoid side effects on the muscle and tendon apparatus still in development. All patients with pre-damaged heart, especially those who have problems with the transmission of stimuli in the heart or suffer from QT syndrome, should not be treated with Avalox® if at all possible in order to avoid worsening of the symptoms in the heart. In patients with myasthenia gravis, Avalox® can lead to a worsening of symptoms, so Avalox® is contraindicated in this case as well. If the patient already has known problems with muscle vision or suffers from epilepsy, Avalox® should not be used.
Interactions with other drugs
The administration of Avalox® together with other drugs that prolong the QT interval (e.g. beta-blockers, erythromycin or tricyclic antidepressants) should be avoided, as this can lead to QT syndrome.