Contraindications | Pantozol®.

Contraindications

Pantozol® must not be taken if there is an allergy or hypersensitivity to pantoprazole or if HIV therapy is carried out with drugs of the active substance atazanavir. Pantozol® must not be taken by children under 18 years of age without express medical advice!

Special Caution

As with the intake of many medications, patients with liver disease also have an increased risk when taking Pantozol®. Therefore, the doctor should regularly check the liver values to detect any deterioration in liver function in good time. If damage is already present, in many cases a maximum daily intake of 20mg Pantozol® per day is indicated.If there is an ulcer in the stomach or duodenum, it is recommended to exclude a possible malignant tumor as a cause.

The doctor should also carry out tests to determine whether the bacterium Helicobacter pylori is present. If this is the case, the administration of antibiotics can be started at the same time. An inflammation of the esophagus should also be clarified by means of a mirror examination.

If the cause of ulcers lies in the increased intake of pain or rheumatism medicines, it should first be checked whether these medicines cannot be discontinued. In the case of a long-term or preventive therapy with Pantozol® , the doctor must carefully weigh up the benefits and risks. Because up to now not all possible risks of a long-term treatment with proton pump inhibitors have been clarified.

Risks

A reduced amount of gastric acid in the stomach, such as is produced when taking Pantozol®, increases the number of bacteria in the stomach. This results in a slightly increased risk of infections of the gastrointestinal tract, such as a salmonella infection. If Pantozol® is taken over a period of more than 3 months, the magnesium level in the blood may drop.

As a result, dizziness, exhaustion and muscle cramps may occur. In addition, there is an increased tendency to fractures (fractures) in the area of the wrist and hip joints, as well as the spinal column, especially when Pantozol® is taken for more than 12 months. Patients with known osteoporosis (‘bone loss’) should therefore urgently inform their doctor about this.