Coxsackie A/B: Or something else? Differential Diagnosis

Diseases to consider for differential diagnosis of coxsackie A virus infection:Infectious and parasitic diseases (A00-B99).

  • Infectious diseases of other genesis

Diseases to be considered for differential diagnosis of Coxsackie B virus infection:

Respiratory system (J00-J99)

  • Mediastinitis – inflammation of the mediastinum (middle pleural space).
  • Pleurisy (inflammation of the pleura)
  • Pneumothorax – collapse of the lungs due to air in the pleural space (physiologically airless space between the pleura and pleura).

Cardiovascular system (I00-I99)

  • Aneurysm dissecans – fissure in an arterial wall (in this case, aorta – main artery) resulting in the formation of a second pathway for blood flow; may rupture (burst)
  • Heart valve defect, unspecified
  • Cardiac arrhythmia
  • Hypertensive crisis – seizure-like increase in blood pressure to values > 200 mmHg.
  • Cardiomyopathy (heart muscle disease)
  • Coronary heart disease
  • Pulmonary embolism – sudden occlusion of an artery supplying the lungs by a thrombus.
  • Myocardial infarction (heart attack)
  • Myocarditis (inflammation of the heart muscle)
  • Roemheld syndrome – reflex cardiac symptoms caused by gas accumulation in the intestines and stomach, usually from overeating or flatulent foods; symptomatology: Extrasystoles (heartbeat occurring outside the physiologic heart rhythm), sinus bradycardia (< 60 heartbeats/min), sinus tachycardia (> 100 heartbeats/min), angina pectoris (chest tightness; sudden onset of pain in the cardiac region), dysphagia (difficulty swallowing), syncope (brief loss of consciousness), vertigo (dizziness).

Infectious and parasitic diseases (A00-B99).

  • Herpes zoster (shingles)

Liver, gallbladder, and bile ducts-pancreas (pancreas) (K70-K77; K80-K87).

Mouth, esophagus (food pipe), stomach and intestines (K00-K67; K90-K93).

  • Boerhaave syndrome – rupture of the esophagus triggered by severe vomiting.
  • Gastroesophageal reflux disease (synonyms: GERD, gastroesophageal reflux disease; gastroesophageal reflux disease (GERD); gastroesophageal reflux disease (reflux disease); gastroesophageal reflux; reflux esophagitis; reflux disease; Reflux esophagitis; peptic esophagitis) – inflammatory disease of the esophagus (esophagitis) caused by the pathological reflux (reflux) of acid gastric juice and other gastric contents.
  • Mallory-Weiss syndrome – clustered longitudinal (elongated) tears of the mucosa (mucous membrane) and submucosa (submucosal connective tissue) of the esophagus occurring in alcoholics, which may be associated with potentially life-threatening hemorrhage of the external esophagus and/or gastric inlet (gastrointestinal hemorrhage/GIB) as a complication
  • Esophageal achalasia – dysfunction of the esophagus due to lack of muscle relaxation.

Musculoskeletal system and connective tissue (M00-M99).

  • Bekhterev’s disease (ankylosing spondylarthritis) – chronic inflammatory spinal disease leading to poor posture.
  • Osteochondrosis – degenerative joint changes, occurring mainly in the cervical / thoracic spine, can lead to pain in the thorax (chest).
  • Tietze syndrome (synonyms: chondroosteopathia costalis, Tietze disease) – rare idiopathic chondropathy of the costal cartilages at the base of the sternum (painful sternal attachments of the 2nd and 3rd ribs) associated with pain and swelling in the anterior thorax (chest) region

Psyche – Nervous System (F00-F99; G00-G99).

  • Bronchial carcinoma (lung cancer)
  • Da Costa syndrome – spontaneously occurring chest tightness, often psychogenically triggered.