Crohn’s Disease: Or something else? Differential Diagnosis

Endocrine, nutritional, and metabolic diseases (E00-E90).

Infectious and parasitic diseases (A00-B99).

Mouth, esophagus (esophagus), stomach, and intestines (K00-K67; K90-K93).

  • Appendicitis (appendicitis).
  • Colitis indeterminata – inflammatory bowel disease (IBD), which does not allow a reliable distinction in ulcerative colitis or Crohn’s disease.
  • Diversion colitis – intestinal disease occurring after surgical immobilization of intestinal segments.
  • Diverticulitis – disease of the large intestine in which inflammation is formed in protrusions of the mucosa (diverticula).
  • Infectious colitis – inflammation of the intestine by bacteria, viruses or parasites such as salmonella.
  • Ischemic colitis – inflammation of the intestine due to insufficient supply of nutrients and oxygen to the intestine, this is mostly due to atherosclerosis (arteriosclerosis, arteriosclerosis) of the arteries supplying the intestines
  • Microscopic colitis or microscopic colitis (synonyms: collagenous colitis; collagen colitis, collagen colitis) – chronic, somewhat atypical proceeding inflammation of the mucous membrane of the colon, the cause of which is unclear and which is clinically accompanied by violent watery diarrhea (diarrhea)/4-5 times a day, even at night; some patients suffer from abdominal pain (abdominal pain) in addition; 75-80% are women/females > 50 years of age; correct diagnosis is only possible with colonoscopy (colonoscopy) and step biopsies (taking tissue samples in the individual sections of the colon), i.e. i.e. by a histological (fine tissue) examination to put.
  • Whipple’s disease (synonyms: Whipple’s disease, intestinal lipodystrophy; Engl : Whipplés disease) – rare systemic infectious disease; caused by the gram-positive rod bacterium Tropheryma whippelii (from the group of actinomycetes), which can affect various other organ systems in addition to the obligately affected intestinal system and is a chronic recurrent disease; symptoms: Fever, arthralgia (joint pain), brain dysfunction, weight loss, diarrhea (diarrhea), abdominal pain (abdominal pain), and more.
  • Food allergy
  • Irritable bowel syndrome (irritable colon)
  • Rectal ulcer (rectal ulcer)
  • Radiation colitis – inflammation of the large intestine, which can occur after radiation, especially in the context of cancer therapy.

Musculoskeletal system and connective tissue (M00-M99).

  • Behçet’s disease (synonym: Adamantiades-Behçet’s disease; Behçet’s disease; Behçet’s aphthae) – multisystem disease of the rheumatic type associated with recurrent, chronic vasculitis (vascular inflammation) of the small and large arteries and mucosal inflammation; The triad (the occurrence of three symptoms) of aphthae (painful, erosive mucosal lesions) in the mouth and aphthous genital ulcers (ulcers in the genital region), as well as uveitis (inflammation of the middle eye skin, which consists of the choroid (choroid), the corpus ciliary (corpus ciliare) and the iris) is stated as typical for the disease; a defect in cellular immunity is suspected

Neoplasms – tumor diseases (C00-D48).

  • Familial adenomatous polyposis (FAP; synonym: Familial polyposis) – is an autosomal dominant inherited disorder. This leads to the occurrence of a large number (> 100 to thousands) of colorectal adenomas (polyps). The probability of malignant (malignant) degeneration is almost 100% (average from the age of 40).
  • Colon carcinoma (colon cancer)
  • Lymphoma – malignant disease originating in the lymphatic system.

Further

  • Pseudoallergies

Medications