Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99).
- Dysgenesis (malformation/development)* * * , unspecified.
- Gonadal dysgenesis* * * – malformation/misdevelopment of the gonads.
- Klinefelter syndrome* – genetic disease with mostly sporadic inheritance: numerical chromosomal aberration (aneuploidy) of the sex chromosomes (gonosomal anomaly), which occurs only in boys or Men occurs; in the majority of cases characterized by a supernumerary X chromosome (47, XXY); clinical picture: large stature and testicular hypoplasia (small testis), caused by hypogonadotropic hypogonadism (gonadal hypofunction); here usually spontaneous onset of puberty, but poor pubertal progress.
- Maldescensus testis* – location of the testis outside the scrotum.
- Noonan syndrome* * – genetic disorder with autosomal recessive or autosomal dominant inheritance that resembles the symptoms of Turner syndrome (short stature, pulmonary stenosis or other congenital heart defects; Low-set or large ears, ptosis (drooping of the upper eyelid ), epicanthal fold (“Mongolian fold”), cubitus valgus/abnormal position of the elbow with increased radial deviation of the forearm to the upper arm).
- Turner syndrome (synonyms: Ullrich-Turner syndrome, UTS)* * – genetic disorder that usually occurs sporadically; girls/women with this peculiarity have only one functional X chromosome instead of the usual two (monosomy X); u. Among other things, with an anomaly of the aortic valve (33% of these patients have an aneurysm/diseased bulging of an artery); it is the only viable monosomy in humans and occurs approximately once in 2,500 female newborns.
Endocrine, nutritional, and metabolic diseases (E00-E90).
- Adrenogenital syndrome (AGS)* * * – autosomal recessive inherited metabolic disease characterized by disorders of hormone synthesis in the adrenal cortex.
- Diabetes mellitus* * * (diabetes).
- Hyperprolactinemia* * * – too high prolactin levels in the blood.
- Hypothyroidism* * * (hypothyroidism) in autoimmune genesis.
- Hyperthyroidism (hyperthyroidism)
- Kallmann syndrome (synonym: olfactogenital syndrome)* * * – genetic disorder that can occur sporadically, as well as be inherited autosomal dominant, autosomal recessive and X-linked recessive; symptom complex consisting of hypo- or Anosmia (decreased to absent sense of smell) in conjunction with testicular or ovarian hypoplasia (defective development of the testis or ovaries, respectively); prevalence (disease frequency) in males 1: 10,000 and in females 1: 50,000.
- Deficiency of growth hormone (synonyms: somatotropic hormone (STH), growth hormone abbreviations: STH, GH, HGH; English : growth hormone, human growth hormone)* * * , unspecified.
- Cushing’s disease* * * – group of diseases leading to hypercortisolism (hypercortisolism; excess of cortisol).
- Cystic fibrosis (ZF)* * * – genetic disease with autosomal recessive inheritance characterized by the production of secretions in various organs that need to be tamed. – genetic disease with autosomal recessive inheritance, which leads to an increase in the viscosity of bodily secretions; the viscous mucus in the bronchi results in chronic cough, bronchiectasis, frequent recurrent (recurring) lung infections and severe pneumonias (lung infections)
Infectious and parasitic diseases (A00-B99).
- Infections* * * , unspecified
Mouth, esophagus (food pipe), stomach, and intestines (K00-K67; K90-K93).
- Celiac disease* * * (gluten-induced enteropathy) – chronic disease of the mucosa of the small intestine (small intestinal mucosa) due to hypersensitivity to the cereal protein gluten.
Musculoskeletal system and connective tissue (M00-M99).
- Autoimmune diseases* * * , unspecified.
Psyche – nervous system (F00-F99; G00-G99).
- Anorexia nervosa (anorexia nervosa)
- Hypothalamic/pituitary granulomas* * * – nodular changes in the area of the hypothalamus or pituitary gland (pituitary gland).
Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99).
- Mumps oophoritis* * (ovarian inflammation due to mumps).
- Mumps orchitis* (testicular inflammation due to mumps).
- Renal failure, unspecified* * *
Injuries, poisoning, and other sequelae of external causes (S00-T98).
- Injuries, unspecified* * *
Other causes
- Chronic diseases, unspecified* * * (e.g. Crohn’s disease).
- Constitutional pubertas tarda* * * .
- Up to 50% of cases in boys
- About 16% of cases in girls
- Radiatio (radiotherapy)* * *
Medication
- Androgens* *
- Anabolic steroids* *
- Chemotherapeutic agents* * *
- Thyroxine (thyroid hormone)* * *
* Boys * * Girls * * * Both sexes
