The following are the most important diseases or complications that may be contributed to by depression:
Endocrine, nutritional, and metabolic disorders (E00-E90).
- Obesity (obesity).
- Diabetes mellitus type 2
- Gestational diabetes (pregnancy diabetes)
- Malnutrition (malnutrition)
- Malnutrition
Factors influencing health status and leading to health care utilization (Z00-Z99).
- Suicide (suicide)
Skin and subcutaneous tissue (L00-L99)
- Herpes zoster (shingles; segmental pain, semigirdular, precedes exanthema/rash).
- Pruritus (itching)
- Pruritus ani (anal itching)
- Seborrheic eczema – greasy, scaly inflammation of the skin; especially in areas of the skin where there are many sebaceous glands, such as the hairy head, face and trunk.
Cardiovascular system (I00-I99).
- Apoplexy (stroke)
- Arterial hypertension (high blood pressure)
- Atherosclerosis (arteriosclerosis, hardening of the arteries)
- Heart failure (cardiac insufficiency)
- Coronary heart disease (CHD)
- Myocardial infarction (heart attack)
- Cerebral atherosclerosis
Mouth, esophagus (food pipe), stomach and intestines (K00-K67; K90-K93).
- Ulcerative colitis (chronic inflammatory bowel disease (colon and rectum)).
- Dysbiosis (imbalance of the intestinal flora).
- Functional dyspepsia (irritable stomach syndrome).
- Glossitis (inflammation of the tongue)
- Caries
- Constipation (constipation)
Musculoskeletal system and connective tissue (M00-M99)
- Osteoporosis (bone loss)
- Back pain?
- Sarcopenia (muscle weakness or muscle wasting).
Psyche – nervous system (F00-F99; G00-G99)
- Drug-induced headache
- Bulimia nervosa (binge eating disorder)
- Dementia – depressive episodes increase dementia risk; new depression > 50 years of age: 2.03-fold higher dementia risk than in patients without new-onset depression
- Erectile dysfunction (erectile dysfunction, ED).
- Extracranial carotid stenosis – narrowing of the carotid artery outside the bony skull (extracranial).
- Insomnia (sleep disturbances) – problems falling asleep, nocturnal wakefulness and early morning awakening resulting in daytime sleepiness.
- Tension-type headache (tension headache).
- Mild cognitive impairment (LKB; also mild cognitive impairment; English : Mild cognitive impairment, MCI).
- Alzheimer’s disease
- Depression is associated with twice the risk of developing Alzheimer’s dementia
- Depression could be a prodromal symptom (symptom indicative of disease) for Alzheimer’s disease rather than a cause of it
- Orgasm disorder
- Post-traumatic stress disorder (PTSD) [due to traumatization of mental illness].
- Psychogenic hyperventilation (increased breathing beyond what is required).
- Transient ischemic attack (TIA) – sudden onset of circulatory disturbance in the brain, resulting in neurological dysfunction that resolves within 24 hours
- Transition to other psychiatric clinical pictures such as mania.
- Obsessive-compulsive disorder
Pregnancy, childbirth and postpartum
- Prematurity*
- Hyperemesis gravidarum (extreme morning sickness) – extreme vomiting during pregnancy.
- Intrauterine growth retardation*
Symptoms and abnormal clinical and laboratory parameters not elsewhere classified (R00-R99).
- Cachexia (emaciation; very severe emaciation).
- Suicidality (suicidal tendencies) – especially high risk on sunny days, which increase the drive to act, which is particularly fatal in patients with major depression; frequency peaks in spring, when the duration of the day increases
- Underweight
Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99)
- Urinary incontinence
Further
- Violence – after accounting for socioeconomic factors such as income and background, depressed individuals were three times more likely than non-depressed individuals to be convicted as violent offenders (3.7% versus 1.2%).
- Partnership conflicts → separations (about 45%).
- Social isolation
- Independent risk factor for increased (cardiovascular) mortality (death rate).
- Shortening of telomeres in leukocytes (white blood cells).
- Increase in pain sensitivity (chronic pain).
* Peripartum depression