Diagnosis
Gout is usually diagnosed on the basis of the physical appearance (clinical appearance) that is characteristic of the disease. Thus, according to the German Rheumatological Society, the diagnosis is considered probable if: as confirmed, if: If a disturbance of the uric acid metabolism and symptoms of acute gout are suspected, laboratory medical examinations are standard. With gout, the uric acid levels in the blood are higher and those in the urine lower (reduced excretion) than normal.
In some cases (approx. 5%), however, the disease is accompanied by normal uric acid levels. As the disease progresses, X-ray examinations can reveal changes in the joints and bones, such as a reduction in the joint space, tissue growths, bone entophi (bone defects) or osteoporosis.
- There is a rapid development of the symptoms within two hours
- At the beginning only one joint (mostly big toe) was affected
- If the symptoms disappear within one to two weeks or
- Additionally, elevated uric acid levels in the blood can be detected and a prompt improvement of symptoms after a typical gout therapy (colchicine administration or NSAIDs, ibuprofen, diclofenac).
- Uric acid crystals can be detected in the synovial fluid.
