Products
Diosmin and hesperidin are commercially available combined in the form of film-coated tablets (Daflon). It has been approved in many countries since 1977.
Structure and properties
Diosmin (C28H32O15, Mr = 608.5 g/mol): Hesperidin (C28H34O15, Mr = 610.6 g/mol):
Effects
Diosmin and hesperidin strengthen veins and protect blood vessels.
Indications
For treatment of edema and other symptoms of venous insufficiency and for hemorrhoids.
Contraindications
The active ingredients are contraindicated in hypersensitivity. For complete precautions, see the drug label.
Interactions
Interactions with other drugs are not known to date.
Adverse effects
Possible adverse effects include digestive discomfort and rarely migraine, malaise, dizziness, or skin reactions.
