Drug-Induced Headache: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate drug-induced headache (drug-induced headache):

  • Diffuse dull aching headache that affects the entire head – often occurs in headache patients with analgesic overuse
  • Frequency increase of migraine and later pulsating headache, possibly nausea (nausea) – common in migraine patients with triptan overuse

Drug-induced headache occurs most commonly with triptans and ergot alkaloids. Analgesics must have a longer duration/frequency of use.

Chronic headache is most common with overuse of barbiturates and opioids.

Warning signs (red flags)