Dry Eye Syndrome (Keratoconjunctivitis Sicca): Or something else? Differential Diagnosis

Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99).

  • Lacrimal gland aplasia – genetic absence of lacrimal glands.

Blood, hematopoietic organs – immune system (D50-D90).

Endocrine, nutritional and metabolic diseases (E00-E90).

Skin and subcutaneous (L00-L99).

Infectious and parasitic diseases (A00-B99).

Musculoskeletal system and connective tissue (M00-M99).

  • Chronic polyarthritis – autoimmune disease of the rheumatic type leading to multiple concurrent joint inflammations.
  • Sjögren’s syndrome (SS; group of sicca syndromes) – autoimmune disease from the group of collagenoses, which leads to a chronic inflammatory disease of the exocrine glands, most often the salivary and lacrimal glands; typical sequelae or complications of the sicca syndrome are:
    • Keratoconjunctivitis sicca (dry eye syndrome) due to lack of wetting of the cornea and conjunctiva with tear fluid.
    • Increased susceptibility to caries due to xerostomia (dry mouth) due to reduced salivary secretion.
    • Rhinitis sicca (dry nasal mucous membranes), hoarseness and chronic cough irritation and impaired sexual function due to disruption of mucous gland production of the respiratory tract and genital organs.

Neoplasms – tumor diseases (C00-D48).

  • Leukemia (blood cancer)

Psyche – nervous system (F00-F99; G00-G99)

  • Cranial nerve lesions, unspecified.

Injuries, poisonings, and other sequelae of external causes (S00-T98).

  • After irradiation in the context of cancer therapy.
  • Burns of the eye with scarring of the ocular surface.
  • Injuries of the eye with scarring of the ocular surface

Medication

Further