Duration of action of Voltaren resinat
The exact time to onset of action of Voltaren resinat® and the exact duration of action depends on the individual person taking the drug. The metabolism of the active ingredient diclofenac, which is used in Voltaren resinat® , takes place largely via the liver. Therefore, a deterioration in liver function (e.g. caused by increased alcohol consumption or other liver diseases) can lead to a different dynamic of action.
Voltaren resinat® is a drug with a fast-acting and a long-lasting component, a so-called retard preparation. In some cases, the pain-relieving effect can occur after as little as 20 minutes, but in most cases the onset of action fluctuates between 45 and 60 minutes. The effect of Voltaren resinat® can last up to 12 hours in individual cases, but for many users it wears off after 8 to 10 hours. If Voltaren resinat® is taken 1 hard capsule a day or 1 hard capsule in the morning and evening as prescribed, no depot effect should develop.This means that the drug does not accumulate in the tissues even after prolonged use.
Contraindications
Contraindications to the use of Voltaren dolo are in the presence of hypersensitivity to diclofenac or other components of the drug: Under certain conditions, such as in the first months of pregnancy, during breast-feeding, in case of a general tendency to allergic reactions, in patients with autoimmune diseases, or if there is a concomitant intake of medication, which have a similar side effect profile to diclofenac (e.g. other NSAIDs such as ibuprofen) or influence the level of diclofenac in the blood (e.g. some antiepileptic drugs such as phenytoin), Voltaren Resinat® should only be taken by a physician, if at all, after consultation and regular monitoring. In addition, alcohol should not be drunk during the entire duration of treatment with Voltaren Resinat®.
- Gastrointestinal bleeding or ulcers
- Blood formation disorders
- Functional disorders of liver or kidneys
- Acute severe bleeding
- Severe heart failure or
- Pregnancy in the second and third trimester.
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