Dydrogesterone

Products

Dydrogesterone is commercially available in the form of film-coated tablets (Duphaston, fixed combination with estradiol: Femoston conti). It has been approved in many countries since 1963.

Structure and properties

Dydrogesterone (C₂₁H₂₈O₂, M_r = 312.4 g/mol)

Effects

Dydrogesterone (ATC G03DB01) has gestagenic properties.

Indications

• Hormone replacement therapy in combination with an estrogen (menopause, ovariectomy).
• Cycle disorders
• Premenstrual syndrome, menstrual cramps.