Laboratory parameters 1st order – obligatory laboratory tests – examination in special laboratory (protection level 4)!
- Pathogen detection from blood:
- RT-PCR (reverse transcriptase-polymerase chain reaction).
- Virus detection from whole blood by surface-enhanced Raman spectroscopy (SERS; SERS test): in this test, gold particles are surrounded by a silicon capsule; antibodies are attached to their surface to bind the virus. The virus can alter Raman scattering, which can be detected by SERS. Ebola detection was successful with a sensitivity of 90.0% at a specificity of 97.9%, giving an overall accuracy of 96.6%. Test duration: approx. 30 min.
- Virus cultivation in the acute phase
- IgM, IgG detection from week 4.
- Small blood count
- Differential blood count
- Inflammatory parameter – CRP (C-reactive protein)
- Fasting glucose (fasting blood sugar)
- Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin.
- Renal parameters – urea, creatinine, cystatin C or creatinine clearance, if necessary.
- Coagulation parameters – PTT, Quick
- Blood cultures