Ewing’s Sarcoma: Classification

The following tumor types are distinguished on the basis of their histologic (fine-tissue) characteristics and site of origin:

  • Classical Ewing sarcoma (EWS).
  • Peripheral malignant primitive neuroectodermal tumor (PPNET).
  • Askin tumor of the thoracic wall (chest wall).
  • Soft tissue Ewing tumor

Lodwick classification

By means of the Lodwick classification, it is possible to assess whether the tumor is benign (benign) or malignant (malignant) on an X-ray. Furthermore, it is suitable for the assessment of progression in the case of aggressive behavior of the tumor.

An index for the growth rate of the bone tumor or an inflammatory process is the reaction visible on the X-ray, i.e. the bone structure is modified locally, regionally or diffusely by the tumor. The visible patterns of destruction are classified into the following main groups:

Grade Growth rate Bone destruction Dignity* Bone tumors
Grade I Purely geographic (circumscribed); boundary definable
  • A
Very slow growing Sclerosis (pathological hardening of here: tissues) and sharp boundary benign Chondroblastoma, enchondroma, fibrous bone dysplasia, nonossifying fibroma, osteoid osteoma
  • B
Slow growing (displacing) Bone distention > 1 cm and/or no sclerosis actively benign Giant cell tumor
  • C
Mean growth rate(locally invasive) Total compact penetration (compacta = outer marginal layer of bone). aggressive benign chondro-, osteo-, fibrosarcomas
Grade II fast growing Geographic, with moth-eaten/permeated (without respect for anatomical boundaries) component predominantly malignant Chondrosarcoma, fibrosarcoma, malignant fibrous histiocytoma, metastases, osteosarcoma
Grade III very fast growing purely moth-eaten or permeative destruction malignant Ewing’s sarcoma

* biological behavior of tumors; that is, whether they are benign (benign) or malignant (malignant)The classification is particularly suitable for tumors of a long bone or small bone. However, it is neither sensitive nor specific, so further diagnostic measures are usually indispensable.