Fall Propensity: Or something else? Differential Diagnosis

Conditions/factors that may cause a tendency to fall:

Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99).

  • Hydrocephalus (hydrocephalus; abnormal enlargement of the fluid-filled fluid spaces (cerebral ventricles) of the brain).

Eyes and eye appendages (H00-H59).

Blood, blood-forming organs – immune system (D50-D90).

  • Anemia (anemia)

Endocrine, nutritional, and metabolic diseases (E00-E90).

  • Hyponatremia (sodium deficiency) – 10-fold increased risk of falls in “asymptomatic “chronic hyponatremia compared with normonatremia.
  • Hypothyroidism (underactive thyroid gland).

Cardiovascular system (I00-I99)

Infectious and parasitic diseases (A00-B99).

  • Infections, unspecified

Musculoskeletal system and connective tissue (M00-M99).

  • Osteoarthritis
  • Restricted mobility, unspecified
  • Rheumatoid arthritis
  • Sarcopenia (muscle weakness or muscle wasting).

Ears – mastoid process (H60-H95)

Psyche – Nervous System (F00-F99; G00-G99).

  • Acute alcohol intoxication and chronic alcohol abuse (alcohol dependence).
  • Dementia (deficit in cognitive, emotional, and social skills; e.g., Alzheimer’s dementia)
  • Depression
  • Diabetic autonomic neuropathy – diabetes-related nervous disease of autonomic nerves.
  • Epilepsy
  • Gait disorders
  • Hydrocephalus (hydrocephalus; pathological enlargement of the liquid-filled fluid spaces (cerebral ventricles) of the brain).
  • Cognitive impairment (human functions related to perception, learning, remembering, and thinking, i.e., human cognition and information processing), not specified
  • Concentration disorders
  • Parkinson’s disease (shaking palsy)
  • Multiple sclerosis (MS)
  • Neurological disorders, unspecified
  • Paresis (paralysis), unspecified
  • Peripheral neuropathy (disruption of one or more peripheral nerves) – including chemotherapy-induced peripheral neuropathy.
  • Polyneuropathy – degenerative disease of the peripheral nerves.
  • Spinal cord damage, unspecified
  • Cystic changes in the cerebral ventricles resulting in sudden and short-lived drop attacks (“fall attack”; sudden fall event with unaffected consciousness due to loss of tone in the lower extremities)

Symptoms and abnormal clinical and laboratory findings not classified elsewhere (R00-R99)

  • Asterixis (“flapping wings,” flutter tremor).
  • Chronic pain – in adults over 50 years of age and presence of multilocular (“in multiple locations”) pain, the tendency to fall is almost doubled compared to peers without pain
  • Gait disorder, unspecified
  • Urinary incontinence (bladder weakness)
  • Syncope – short-lasting fainting due to an undersupply of oxygen to the brain.
  • Vertigo (dizziness; e.g., labyrinthitis, Meniere’s disease).

Further

  • Physiological changes in old age*

Medication

  • Medication side effects
    • Alpha blockers-significantly more men fell after starting therapy than men in the control group (1.45 versus 1.28%). Relatively, the difference was about 12%; absolutely, it was only 0.17%; bone fractures were recorded in 0.48% of patients on alpha blockers and in 0.41% without (the difference was significant)
    • Benzodiazepines, phenothiazines, tricyclic antidepressants; antihypertensives – people who had already had a fall[1] were particularly at risk); another study was unable to confirm the association with antihypertensives: in fact, it was able to demonstrate a significantly low risk of falls resulting in injury for ACE inhibitors and calcium antagonists; another study was also able to demonstrate a lower risk of falls for RAAS inhibitors
  • Polypharmacy (> 6 prescribed medications).
  • Other drugs see below delirium

* Physiological changes in old age include:

  • General weakness
  • Orthostatic hypotension – drop in blood pressure associated with standing up.
  • Alteration of attention, coordination and speed
  • Decreased proprioception (perception of depth sensitivity and body position in space).
  • Decreased vision
  • Increasing postural instability