Fatigue: Or something else? Differential Diagnosis

Respiratory System (J00-J99)

  • Influenza – group of acute febrile upper respiratory tract infections.
  • Pneumonia (inflammation of the lungs)
  • Sinusitis (sinusitis)

Blood, blood-forming organs – immune system (D50-D90).

  • Anemia (anemia)
  • Iron deficiency anemia (anemia caused by iron deficiency).
  • Hemolytic anemia – forms of anemia (anemia) characterized by increased degradation or decay (hemolysis) of erythrocytes (red blood cells), which can no longer be compensated by increased production in the red bone marrow.

Endocrine, nutritional and metabolic diseases (E00-E90).

  • Meulengracht’s disease (disorder of bilirubin metabolism).
  • Wilson’s disease (copper storage disease) – autosomal recessive inherited disorder in which one or more gene mutations disrupt copper metabolism in the liver

Skin and subcutaneous (L00-L99).

  • Pityriasis rosea (rose lichen) – harmless, non-infectious inflammatory dermatoses (skin disease).

Cardiovascular system (I00-I99).

Infectious and parasitic diseases (A00-B99).

  • Influenza
  • Keratoconjunctivitis epidemica (KC) – viral disease of the conjunctiva (conjunctiva) and the cornea (Latin cornea, Germanized also cornea, Greek keratos) of the eye.
  • Malaria (tropical disease)
  • Norovirus infection – infectious disease of the gastrointestinal tract (gastrointestinal tract).
  • Plague
  • Rotavirus infection – infectious disease of the gastrointestinal tract (gastrointestinal tract).
  • Toxoplasmosis – infectious disease caused by Toxoplasma gondii, which belongs to the protozoa.
  • Viral meningitis (meningitis caused by viruses).
  • West Nile fever – infectious disease, which is one of the zoonoses (infectious diseases transmissible from animal to human; animal diseases).

Liver, gallbladder, and biliary tract – pancreas (pancreas) (K70-K77; K80-K87).

  • Hepatitis (inflammation of the liver)

Musculoskeletal system and connective tissue (M00-M99).

  • Dermatomyositis – inflammatory muscle disease (myositis) that also affects the skin (dermatitis).
  • Eosinophilic granulomatosis with polyangiitis (EGPA) – granulomatous inflammation of small to medium-sized blood vessels, in which the affected tissue is infiltrated by eosinophilic granulocytes.
  • Granulomatosis with polyangiitis (GPA) – necrotizing vasculitis (vascular inflammation) of small to medium-sized vessels (small-vessel vasculitides), which is accompanied by granuloma formation in the upper respiratory tract (nose, paranasal sinuses, middle ear, oropharynx) as well as the lower respiratory tract (lungs)
  • Polymyalgia rheumatica (PMR) – inflammatory rheumatic disease; belongs to the group of vasculitides.
  • Poliomyelitis – inflammatory systemic disease of the skeletal muscles.
  • Rheumatoid arthritis – chronic inflammatory multisystem disease, usually manifested in the form of synovitis (inflammation of the synovial membrane).
  • Sjögren’s syndrome – group of collagenoses leading to chronic inflammatory disease or destruction of the exocrine glands, with the salivary and lacrimal glands most commonly affected.
  • Vasculitides – inflammatory rheumatic diseases characterized by a tendency to inflammation of the (mostly) arterial blood vessels.

Neoplasms – tumor diseases (C00-D48).

  • Leukemias (blood cancers), e.g.
    • Acute mycological leukemia
    • Chronic lymphocytic leukemia
  • Tumor diseases (cancer), without further details, eg.

Ears – mastoid process (H60-H95).

  • Otitis media (inflammation of the middle ear)

Psyche – nervous system (F00-F99; G00-G99)

Pregnancy, childbirth and puerperium (O00-O99)

Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).

  • Cachexia – emaciation of the organism (emaciation) due to profound disturbance of one or more organ functions.
  • Cardiomegaly – enlargement of the heart beyond normal.
  • Underweight

Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99)

  • Nephrotic syndrome – collective term for symptoms associated with various diseases of the glomerulus (renal corpuscles); symptoms include proteinuria (increased excretion of protein in the urine) with a loss of protein; hypoproteinemia, peripheral
  • Obstructive uropathy and refluxuropathy – urinary transport disorders (urinary retention/stasis).
  • Pyelonephritis (inflammation of the renal pelvis).

Injuries, poisonings, and other consequences of external causes (S00-T98).